The vagus nerve is made up of an intricate neural network that maintains homeostasis and equilibrium in important processes as well as interfacing with inflammatory, autonomic, mood and pain regulation. Learn how we are utilising the neuromodulatory effects of the vagus nerve to improve patient outcomes and increase quality of life.



Fibrillation ​


TREAT AF II: A Randomised Clinical Trial



BRIDGE AF: A Randomised Clinical Trial



TREAT AF (Transcutaneous Electrical Vagus Nerve Stimulation to Suppress Atrial Fibrillation): A Randomised Clinical Trial

Stavrakis et al. Clinical Electrophysiology 2020





Failure ​


TREAT-HF Low Level Tragus Stimulation in Acute Decompensated Heart Failure: A Randomized Clinical Trial 



TRANSFER HF: A Randomized Clinical Trial Ongoing 



TECO-HF (Neuromodulation of Inflammation and Vascular Function in Systolic Heart Failure): A Randomized Clinical Trial 



Neuromodulation to Treat Patients With Heart Failure With Preserved Ejection Fraction

Stavrakis et al. J Am Heart Assoc 2022


Effects of low-level tragus stimulation on endothelial function in heart failure with reduced ejection fraction

Dasari et al. Journal of Cardiac Failure 2021








Non-Invasive vagal nerve stimulation in autonomic disorders



Non-Invasive vagal nerve stimulation in Long Covid syndrome

Expected 2022


Vagus Nerve Stimulation as a Treatment of Long Covid

Expected 2022


Transcutaneous Auricular Vagus Nerve Stimulation (tVNS) can Reverse the Manifestations of the Long-COVID Syndrome: A Pilot Study

Verbanck et al. Frontiers in Neurology and Neuroscience 2021





Improvement of memory-based reading recall using transcutaneous auricular vagus nerve stimulation     

Thakkar et al. 2021 


The effects of taVNS on novel language learning in young adults 

Thakkar et al. 2020


The effect of transcutaneous auricular vagus nerve stimulation on reading comprehension 

Richardson et al. 2020





Science of Modulating the Nervous System​





Transcutaneous vagal nerve stimulation synergizes with radiotherapy by ameliorating the anti-tumor response in lung cancer     



Effects of non-invasive vagal nerve stimulation on radiation-induced inflammation and cancer prognosis     

Reijmen et al. 2020 


+ >20 Stealth Studies